In our opinion, this patient developed meigs syndrome in relation to the solid fibromalike tumor of the right ovary. Other signs and symptoms can include hearing loss, feeding problems, respiratory tract abnormalities, small chin, and small head size. The rare clinical presentation of large volume ascites and hydrothorax associated with benign ovarian tumours, is referred to as meigs syndrome and was first described in 1937. The initial management centered on the treatment of the pulmonary. We describe here 2 patients with meigs syndrome and 2 pa tients with pseudomeigs syndrome. If an internal link led you here, you may wish to change the link to point directly to the intended article. Pseudo meigs syndrome refers to a clinical syndrome of pleural effusion, ascites associated with an ovarian tumor that is not a fibroma or a fibromalike tumor. A group of symptoms that collectively indicate or characterize a disease, disorder, or other condition considered abnormal.
The pseudo meigs syndrome cases have in common the cure of the pleural effusion after the removal of the lesion. This is a case report of meigs syndrome with elevated ca 125 level. Raised cancer antigen ca125 levels can also be found in a few cases 12. We believe that this episode was incidental to a preexisting meigs syndrome. Full text get a printable copy pdf file of the complete article 1. Meigs syndrome with marked elevation of ca125 is an unusual clinical condition reported in 27 cases in the literature. Meige syndrome nord national organization for rare disorders. This presentation may result in a mis diagnosis of malignant ovarian cancer in elder ly patients which lead to unnecessary exten sive surgery. Meigs syndrome is defined as a hydrothorax with ascites and a pelvic tumor, both of which resolve on removal of the tumor. The features of this disease were first described by meigs and cass in 1937. Meigs syndrome should be considered in the diagnosis of malignant ovarian cancer and pathological biopsies are.
Dec, 2016 pseudopseudo meigs syndrome may occur in patients with systemic lupus erythematosus and describes the presence of pleural effusions, ascites and an elevated ca 125 level 9, 10. Use the serum albumin to ascitic albumin difference serum albumin minus ascites albumin to help differentiate the cause of ascites. We report a patient with a large twisted ovarian fibroma associated with meigs syndrome, abdominal pain and severe. Meigs syndrome is defined as the presence of ascites and pleural effusion in association with a benign, usually solid ovarian tumor. Such straight connection allows classifying different tumors as being the cause of only one syndrome 1,3. Meigs syndrome usually occurs in postmenopausal women and resolves following removal of the. Meige syndrome synonyms, meige syndrome pronunciation, meige syndrome translation, english dictionary definition of meige syndrome. There is no classification system established for meigs syndrome.
In 1934, salmon described the association of pleural effusion with benign pelvic tumors. Meigs syndrome is named after joe vincent meigs, an american gynecologist who defined meigs syndrome as the presence of ascites, hydrothorax, association with benign ovarian tumor. Metastatic tumours of the ovary commonly originate in the gastrointestinal tract. Meiergorlin syndrome mgs is a very rare inherited condition characterized by very small ears and ear canals, short stature, and absent or very small kneecaps patellae. You must choose a different option for each of your three enrichment choices ex. Meigs syndrome symptoms, complications, treatment, surgery. While, pseudomeigs syndrome is characterized by the coexistence of pleural effusion, ascites and other ovarian or pelvic tumors. Below are the links to the authors original submitted files for images. Other variants of meigs syndrome include pseudomeigs. Ca125 is a widely accepted tumor marker of ovarian carcinoma. Medical care of patient with meigs syndrome involves paracentesis and thoracentesis for ascites and pleural effusion respectively.
Joe vincent meigs, 18921963, american gynaecologist. Get a printable copy pdf file of the complete article 161k, or click on a page image below to browse page by page. The pathogenesis of the production of ascites and pleural effusion in this syndrome remains unknown. In 1937, meigs and cass1 reported seven cases in which a benign fibroma of the ovary was accompanied by a. If you have problems viewing pdf files, download the latest version of adobe reader. Meigs syndrome is defined as the coexistence of benign ovarian fibroma or fibromalike tumor, ascites, and pleural effusion. As far as we can discover, only two cases of meigs syndrome have been observed at. Our mission is to provide a rigorous liberal arts curriculum that will allow our capable learners to perform at high standards of academic and social development. This is known as meigs syndrome, a name first suggested by rhoads and terrel in 1937. Meige syndrome is a rare, neurological condition characterized by blepharospasm abnormal movement of the eyelids. Meigs syndrome triad benign ovarian tumor fibroma, pleural. Feb 17, 2015 if you have problems viewing pdf files, download the latest version of adobe reader. We are an academic middle school for 5th to 8th grade students. In medicine, meigs syndrome, also meigs syndrome or demonsmeigs syndrome, is the triad of ascites, pleural effusion, and benign ovarian tumor ovarian fibroma, fibrothecoma, brenner tumour, and occasionally granulosa cell tumour.
Meige syndrome genetic and rare diseases information center. Pleural effusion in meigs syndrometransudate or exudate. Get a printable copy pdf file of the complete article 656k, or click on a page image below to browse page by page. Nov 14, 2016 therefore, the prognosis and etiology of pseudomeigs syndrome caused by ovarian metastasis from colorectal cancers remain unclear. Meigs syndrome resolves after the resection of the tumor. This work is licensed under the creative commons attribution international license cc by. C a s e r e p o r t a 3 0yearold woman was hospitalized in our gynecology department for pelvic pain and respiratory distress. Meigs syndrome is defined as the coexistence of bening ovarian fibroma, hydrothorax and ascites. Large twisted ovarian fibroma associated with meigs syndrome. As far as we can discover, only two cases of meigs syndrome have been observed at michael reese hospital in many years.
Meigs syndrome not to be confused with meige syndrome or meige diseasein medicine, meigs syndrome, also meigs syndrome or demons meigs syndrome, is the triad of ascites, pleural effusion, and benign ovaria. The causes of the ascites and pleural effusion are poorly understood. We report here a rare case of pseudomeigs syndrome caused by ovarian metastases from sigmoid colon cancer with longterm survival. Meigs syndrome 1937 meigs syndrome is defined as the presence of ascites and pleural effusionhydrothorax in association with a benign, usually solid, ovarian tumor usually an ovarian fibroma 8090% sarria hp et al. Atypical meigs syndrome, characterized by a benign pelvic mass with rightsided ple.
On the contrary, pseudo meigs syndrome is characterized by the coexistence of hydrothorax, ascites and other ovarian usually malignantor pelvic tumors. The torsion of the large cystic tumor produced the acute symptoms which forced the patient to seek relief. Meigs syndrome describes the occurrence of a solid benign ovarian tumor, usually a fibroma, along with the presence of ascites and pleural effusions. Longterm survival in pseudomeigs syndrome caused by. In contrast, pseudomeigs syndrome is defined as the coexistence of other ovarian or pelvic tumors, ascites, and pleural effusion. Meigs syndrome, a disorder of the female reproductive system. The meigs syndrome is a rare but wellknown syndrome defined as the triad of benign solid. Krukenberg tumours are metastatic ovarian neoplasms originating exclusively in the. Meigs syndrome also known as meigscass syndrome is defined as the triad of ascites, pleural effusion, and benign ovarian tumor. Pdf an elevated serum ca125 level in association with a pelvic mass, pleural effusion, and massive ascites usually signifies a dismal. Bila pasien menaglami luka bakar luas dan menunjukkan gejalagejala syok hipovolemik, bantu dokter dengan pemasangan kateter vena sentral.
Meigs syndrome is the triad of ovarian tumor chapter 205, ascites, and pleural effusion. For language access assistance, contact the ncats public information officer. Meigs syndrome and pseudo meigs syndrome both presents with hydrothorax and ascites. Large twisted ovarian fibroma associated with meigs. Not to be confused with meige syndrome or meige disease. Meigs county chamber of commerce 423 3345496 meigs county department of childrens services 423 2984618 meigs county department of human services 423 3345787 meigs county mayor 423 3345850 meigs county schools 423 3345793 niota city hall senior citizens home 423 5682584 town of decatur 423 3345716 legal services. This disambiguation page lists articles associated with the title meigs. Meigs syndrome triad benign ovarian tumor fibroma, pleural effusion, and ascites, with disappears after removal of pelvic tumor. Tardive dystonia truncal dystonia is most typical form focal and segmental dystoniableparopspams, cervical dystonia and oromandibular occur and extremities can be involved mf younger age seen after chronic use of dopamine blocking agents median duration is 5. Meigs syndrome is a strange clinical entity that is also considered to be an uncommon complication of fibroma of the female genital tract.
Meige syndrome nord national organization for rare. Meigs syndrome is defined as the presence of a benign ovarian tumor with pleural effusion and ascites that resolve after removal of the tumor. Atypical meigs syndrome consists of a benign pelvic mass with a rightsided pleural effusion but no ascites present. Meigs syndrome is defined as the presence of ascites and pleural effusionhydrothorax in association with a benign, usually solid, ovarian tumor usually an ovarian fibroma 8090% sarria hp et al. Because the transdiaphragmatic lymphatic channels are larger in diameter on the right, the pleural effusion is classically on the right side.
In medicine, meigs syndrome, also meigs syndrome or demonsmeigs syndrome, is the triad of ascites, pleural effusion, and benign ovarian tumor. A syndrome characterised by a solid ovarian tumour, usually a fibroma, accompanied by ascites and hydrothorax. Read more about symptoms, diagnosis, treatment, complications, causes and prognosis. However, patients with meigs syndrome can also have elevated serum ca 125 levels. Ovarian fibromas constitute the majority of the benign tumors seen in meigs syndrome.
Fellows of the gsa are honored for their distinguished contributions to the geosciences. Collectively, the many types of primary lymphedema affect an estimated 1 in 100,000 people younger than 20. However, the optimal approach for its management has not been sufficiently investigated. Meigs syndrome includes findings of an adnexal mass, ascites, and pleural effusions. Pseudomeigs syndrome a term given by meigs is the same as true meigs syndrome, except that in the pseudomeigs syndrome the tumor may be in the ovary, tubes, uterus or round ligament. Case presentation 43f, p0, presented on 101915 w sob.
Meigs syndrome consists of ascites, hydrothorax and a malignant ovarian tumour. The effusion, which is usually large and on the right side, is formed when fluid moves from the abdomen to the pleural space through diaphragmatic defects. Meigs syndrome, however, is a diagnosis of exclusion, only after ovarian carcinoma is. History in 1934, salmon described the association of. Thoracic endometriosis jonathan parks, md kings county hospital center january 21, 2016. The term nonclassic meigs syndrome was applied for patients with ascites and pleural effusion associated with benign ovarian, fallopian tube, or broad ligament tumors other than those included in the definition of classic meigs syndrome table table1. Meigs syndrome is a rare neoplastic disease characterized by the clinical triad of benign ovarian tumor typically, ovarian fibroma or. Meige syndrome definition of meige syndrome by the free. See chapter, peritoneal abdominal paracentesis for more details. Pathology entities that have been reported to result in pseudo meigs syndrome inclu. Fortunately, it was discovered that she had benign cystic teratoma of the ovary with ascites and hydrothorax meigs syndrome. Meigs syndrome, however, is a diagnosis of exclusion, only after ovarian carcinoma is ruled out. Meigs syndrome not to be confused with meige syndrome or meige diseasein medicine, meigs syndrome, also meigs syndrome or demonsmeigs syndrome, is the triad of ascites, pleural effusion, and benign ovaria. This is a syndrome with the trio of ascites, pleural effusion excess fluid in the pleura.
Federal forms have changed this year, and are now considered 1040 packets, which are also available. Pseudomeigs is a variant not possessing the original tumor cell types described by meigs. In the vast majority 8090% of cases, the primary tumor is an ovarian fibroma. Meigs syndrome is a rare condition, defined as the coexistence of benign ovarian fibroma, pleural effusion and ascites. A case of meigs syndrome with preceding pericardial. The majority of cases usually resolve after surgical resection of the ovarian mass. Jun 24, 2014 the meigs syndrome is a rare but wellknown syndrome defined as the triad of benign solid ovarian tumor, ascites, and pleural effusion. Meigs is recognized for his research on the interplay of rock uplift.
Meigs syndrome represents a triad of pleural effusion, ascites, and an ovarian tumor, which is usually benign, occurring together. Ascites, hydrothorax, meigs syndrome, pathology, tumor marker. Treatment of this syndrome is based on vascular filling, sedation, analgesia, the reverse trendelenberg position. A condition is termed pseudo meigs syndrome when it is associated with any other type of ovarian tumor, such as a mature teratoma, struma ovarii, metastatic ovarian tumor, or leiomyoma 8. Meige syndrome is a rare neurological movement disorder characterized by involuntary and often forceful contractions of the muscles of the jaw and tongue oromandibular dystonia and involuntary muscle spasms and contractions of the muscles around the eyes blepharospasm. In meigs syndrome the classical findings of ascites, pleural effusion in combination. Mar 24, 2016 meigs syndrome is defined as the triad of benign ovarian tumor with ascites and pleural effusion that resolves after resection of the tumor. Meige disease is the most common type of primary lymphedema. People with mgs may also have characteristic facial features including a small mouth. N2 the association of a benign ovarian tumor with ascites and hydrothorax that resolve after tumor resection is known as meigs syndrome, and its importance was first emphasized by meigs and cass in 1937. Pdf meigs syndrome represents a triad of pleural effusion, ascites, and an ovarian tumor, which is usually benign, occurring together. Therefore, the renal pelvis transitional cell carcinomacan result in the pseudo meigs. The authors report a case of meigs syndrome with elevated ca 125 level.
Links to pubmed are also available for selected references. Simultaneously with elevated tumor marker and hydrothorax in. We describe a rare case of pseudo meigs syndrome caused by a uterine leiomyosarcoma not reported in the literature so far. The more frequently observed type of ovarian tumor is the fibroma. Meige syndrome genetic and rare diseases information. Meigs syndrome consists of a benign ovarian tumor accompanied by ascites and hydrothorax. These enrichment options will last for one semester 8 sessions, unless you are on student council this option will be year long. The patient was a 46yearold woman with right pleural effusion, ascites. Meigs syndrome definition of meigs syndrome by medical. Meigs syndrome an accumulation of fluid in the abdomen or in the space between the lungs and the chest wall pleural effusion associated with a fibroma or other tumour of an ovary. Ovarian fibroma represents 2 to 5% of ovarian tumor and out of this only 1 to 2% of cases present as meigs syndrome.
Meigs syndrome presenting with axillary vein thrombosis and. Aside from pleural effusion and ascites, pericardial effusion is rarely observed in meigs syndrome. We report a patient with a large twisted ovarian fibroma associated with meigs syndrome, abdominal pain and. Meigs syndrome is named after joe vincent meigs, an american obstetrician and gynaecologist 18921963, who reported a case series in 1937 and subsequently described the syndrome. Meigs proposed limiting the diagnosis of meigs syndrome to benign and solid ovarian tumours with ascites and pleural effusion, and with the condition that removal of the tumour cures the patient without recurrence. Nephrotic syndrome meigssyndrome, ovarian hyperstimulation peritonealdialysis myxoedema exsudate tumor infection pulmonary embolism lung infarction abdominaldiseases autoimmun diseases eosinophilic pneumonia asbest irradiation eosophagealperforation haemothorax chylothorax empyema thoracis. Nonclassic meigs syndrome and demonsmeigs syndrome. Pseudopseudo meigs syndrome ppms is a newly emerging. January 21, 2016 kings county hospital center thoracic. The meigs syndrome is a rare but wellknown syndrome defined as the triad of benign solid ovarian tumor, ascites, and pleural effusion. Meigs syndrome is defined as the triad of benign ovarian tumor with ascites and pleural effusion that resolves after resection of the tumor. A case report divya kallarackal, dharampal singh abstract introduction.
Genetic and rare diseases information center gard po box 8126, gaithersburg, md 208988126 tollfree. A 47yearold woman presented with abdominal distention of 1month duration. Meigs syndrome symptoms, causes, treatment, complications, surgery information. Meigs syndrome is characteristically associated with ovarian fibroma whereas pseudo meigs syndrome is associated with any ovarian or pelvic tumors, other than ovarian. The condition is being treated with botulinum toxin. On the contrary, pseudomeigs syndrome is characterized by the coexistence of hydrothorax, ascites and other ovarian usually malignantor pelvic tumors. Demonsmeigs syndrome is a benign disease with a good prognosis. Dear 4her and family, all spring and these early moments of summer you have been attending 4h meetings and events, giving demonstrations in club meetings, attending summer camp and working on your 4h projects.
Dec 11, 2015 nonclassic meigs syndrome and demonsmeigs syndrome. Our patients case is a very unusual presentation of borderline ovarian tumour with a huge amount of ascites. Full text full text is available as a scanned copy of the original print version. For unknown reasons, this condition affects females about three times as often as males.
89 726 1506 1087 1320 1445 324 1245 757 885 1252 263 1026 371 222 1431 300 1289 1046 753 1440 390 31 1356 223 632 913 1646 734 104 395 1013 1164 264 1012 818 399 1516 515 195 242 1113 905 1345 1271